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首页- Products - Others - Other Targets - 4-Nitrophenyl α-D-galactopyranoside

4-Nitrophenyl α-D-galactopyranoside

CAS No. 7493-95-0

4-Nitrophenyl α-D-galactopyranoside ( PNP-alpha-D-Gal | PNP-α-D-Gal )

产品货号. M27057 CAS No. 7493-95-0

4-硝基苯基 α-D-吡喃半乳糖苷 (PNP-α-D-Gal) 是 4-硝基苯基 (pNP) 吡喃葡萄糖苷的人工底物,用于检测 α-半乳糖苷酶活性。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG ¥381 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    4-Nitrophenyl α-D-galactopyranoside
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    4-硝基苯基 α-D-吡喃半乳糖苷 (PNP-α-D-Gal) 是 4-硝基苯基 (pNP) 吡喃葡萄糖苷的人工底物,用于检测 α-半乳糖苷酶活性。
  • 产品描述
    4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantly increased when 4-Nitrophenyl α-D-galactopyranoside is used as substrates.(In Vitro):Using 4-nitrophenol (pNP)-glycopyranosides as pseudosubstrates, the amount of liberated pNP from the 4-Nitrophenyl α-D-galactopyranoside is significantly higher than that from the other pNP-glycopyranosides at pH 4.0 whereas no activity was detected at pH 7.0. The digestion assays using pNP glycopyranosides as artificial substrates show that yielding liberated galactose residues from 4-Nitrophenyl α-D-galactopyranoside mainly at pH 4.0, i.e. the pH level where yield threshold is decreased at most.
  • 体外实验
    Using 4-nitorophenol (pNP)-glycopyranosides as pseudosubstrates, the amount of liberated pNP from the 4-Nitrophenyl α-D-galactopyranoside is significantly higher than that from the other pNP-glycopyranosides at pH 4.0 whereas no activity was detected at pH 7.0. The digestion assays using 4-nitrophenyl (pNP) glycopyranosides as artificial substrates shows that yieldin liberated galactose residues from 4-Nitrophenyl α-D-galactopyranoside mainly at pH 4.0, i.e. the pH level where yield threshold is decreased at most.
  • 体内实验
    ——
  • 同义词
    PNP-alpha-D-Gal | PNP-α-D-Gal
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Alkyl-Chain| Non-cleavable
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    7493-95-0
  • 分子量
    301.25
  • 分子式
    C12H15NO8
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?H2O : 16.67 mg/mL (55.34 mM)
  • SMILES
    O[C@@H]1[C@H](O)[C@@H](O)[C@@H](OC2=CC=C([N+]([O-])=O)C=C2)O[C@@H]1CO
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
产品手册
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